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Familial patterns of microbial infection in periodontitis.


The purpose of this study was to find evidence of familial aggregation of periodontal bacteria namely B. forsythus, C. rectus, P. gingivalis and P. intermedia. Data available for study consisted of 264 families with 220 parent-child pairs, 129 mother-child pairs, 91 father- child pairs and 99 sib pairs, collected as part of the North Carolina Piedmont Dental studies. Analytic approaches included regressive modeling with and without covariate adjustments; specific hypotheses tested included gender specific parental effects on bacterial status of children. Assessment of covariate relationships led to the performance of race specific analyses, with interesting results.