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Interaction of Fusobacterium nucleatum with host immune system.


Fusobacterium nucleatum is a gram-negative anaerobe that is the principal and most frequent isolate of periodontal diseases. Like any other infectious agents, F. nucleatum requires successful colonization of the host, invasion beyond the mucosal surface, and evasion of host defenses. Each of these steps may be mediated by different virulence factors. This study focuses on two suspected virulence factors of this bacterium: the Fc receptors and the lectin -like adhesin proteins.