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Combined effects of diet and exercise intervention on self -reported knee pain associated with osteoarthritis.


Background. Osteoarthritis ranks among the top three health care problems in the developed world. It is a leading cause of disability in the elderly population and the relative economic impact of this condition has reached 2.5 percent of the gross national product. Lifestyle changes including nutrition and physical activity are now recommended as the first line of treatment for osteoarthritis. Vitamin A, C, D, and E have shown beneficial effects because of their anti-oxidant capacity and role in the metabolism of bone and cartilage. The American College of Rheumatology recommends moderate intensity exercise as it helps to decrease pain, increase muscle strength and improve physical function. However, the combined impact of dietary and exercise intervention needs to be investigated further.